عکس
دکتر کیانوش ملک زاده تعداد بازدید: 526
آخرین بروز رسانی : 1395/12/22
ویرایش پروفایل
مرتبه علمی : استادیار
مدرک تحصیلی : دکتری تخصصی بیوتکنولوژی پزشکی
گروه آموزشی : ژنتیک پزشکی دانشکده پزشکی
محـل خـدمت : -
سـمت اجرایی : رئیس مرکز تحقیقات پزشکی مولکولی
ایمیل : K.malekzadeh@hums.ac.ir
تلفن : 0763-3668156
فایل رزومه : دریافت فایل (بروز رسانی شده)


1)  Sobti RC; Kordi Tamandani DM; Shekari M; Kaur P; Malekzadeh K; Suri V. (2008) Interleukin-1 beta gene polymorphism and risk of cervical cancer. Int. J Gynaecol Obstet. 101 (1): 47-52.

2) Shekari M;  Sobti RC;  Kordi Tamandani  DM; Malekzadeh K; Kaur P; Suri V. (2008) Association of genetic polymorphism of the DNA base excision repair gene (APE-1 Asp/148 Glu) and HPV type (16/18) with the risk of cervix cancer in north Indian population. Cancer Biomark. 4 (2):63-71.

3) Sobti RC; Shekari M; Kordi Tamandani  DM; Malekzadeh K; Suri V. (2008) Association of Interleukin-18 Gene Promoter Polymorphism on the Risk of Cervix Carcinogenesis in North Indian Population. Oncology Research, 17(4):159-166.

4) Malekzadeh K**; Sobti RC; Nikbakht M;  Shekari M; Hosseini SA; Kordi DM.; Singh S.K. (2009) Methylation pattern of Rb1 and Casp-8 promoter and its impact on their expression in bladder cancer, Cancer Investigation 27 (1) :70-80.

5) Sobti  R.C; MalekZadeh K**; Nikbakht M; Sadeghi IA;  Shekari M;  Singh S.K. (2009) Hyper-methylation mediated partial transcriptional silencing of DAP-kinase gene in bladder Cancer. Biomarkers. 2009 Dec 3.

6) MalekZadeh K**;  Nikbakht M.; Asadi Sadeghi I; Sobti  R.C; Singh S.K. (2009) Over-expression of IL-13 in patients with bladder cancer. Cancer Investigation Feb;28(2):201-7

7) Ali Hosseini S, Sobti RC, Malekzadeh K, Singh SK, Joshi K. (2010) Frequency of P16INK4a and P14ARF genes methylation and its impact on bladder cancer cases in north Indian population. Disease Markers; 8(6):361-8.

8) Mohsen Nikbakht, Jha Abimanu Kumar, Kianoosh MalekZadeh, Marjan Askari, Neena Caplash, Marwa Ram Kumar, Deepak Kaul, Jagdeep Kaur (2011) No association of Folate-related and Methionine synthesis genes variant in the development and progression of childhood ALL among North Indian Population. International Journal of Hematology and Oncology and stem cell Therapy, 5(1): 20-29.

9)  Shekari M; Kordi Tamandani DM; MalekZadeh K; Sobti R.C; Suri V.(2012) Effect of anti-inflammatory (IL4, IL10) cytokine genes in relation to risk of cervix carcinoma. Am J Clin Oncol. (35)6:514-519.

10) M.Nikbakht, K. MalekZadeh** A. Kumar Jha, M. Askari, R.K. Marwaha, D.Kaul, J.Kaur (2012) Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood all in north india. Experimental Oncology 34(1):43-48

11) Mahin Jamshidi, Mohammad Shekari, Abdol Azim Nejatizadeh, Keyanoush Malekzadeh, Mahnaz Baghershiroodi, Parivash Davudian, Farzaneh Dehghan, Froogh Jamshidi (2012) The impact of human papillomavirus (HPV) types 6, 11 in women with genital warts. Archives of Gynecology and Obstetrics (286)5:1261-7

12) IzadpanahQeshmi Fatemeh, Javadpour Sedigheh ,MalekZadeh Kianoosh, Rahimzadeh Mahsa,TamdoniJahromi Saeid. (2013) Isolation and identification of L-asparaginase producing actinomycetes from Persian Gulf Journal of Hormozgan University of Medical Sciences; 18(2)121-129.

13) IzadpanahQeshmi Fatemeh, Javadpour Sedigheh ,MalekZadeh Kianoosh, Rahimzadeh Mahsa,TamdoniJahromi Saeid, Eslami Majid. (2013)  Isolation and molecular identification of L-asparaginase producing bacteria from Persian Gulf. Journal of Microbial World 2013, 6(3): 237-245.

14)  Izadpanah Qeshmi F, Javadpour S., Malekzadeh K** Tamadoni Jahromi S, Rahimzadeh, M. (2014) Persian Gulf is a bioresource of potent L-asparaginase producing bacteria: Isolation & Molecular differentiation. Int. J. Environ. Res., 8(3):813-818.

15) Haniah  Solaimani 1, Nepton Soltani *, Kianoosh MaleKzadeh **, Shahla Sohrabipour, Sema Nasri. (2014) Modulation of GLUT-4 expression by oral administration of Mg2+ to control sugar level in STZ-induced diabetic rat. Can. J. Physiol. Pharmacol. 92: 438–444

16) Soleimani Hanieh., MalekZadeh Kianoosh**, Shekari Mohammad, Paran Faridehsadat, Bazmjou Maryam, Namjou Elham,Jafari Masoumeh. (2014) A case report of Hemoglobin Hamadan in Hormozgan Province. Sci J Iran Blood Transfus Organ 11(3): 252-256.

 

17) Gholam-Reza Ameri; Kianoosh Malekzadeh**, Zahra Noor-Mohamadi; Mohammad Shekari; Habibollah Turki; Hanieh Solaimani. (2014) The Impact of Genetic Variants of Cytokines of IL-18 & IFN-γ on Severity of Malaria & Quality of treatment  Journal of Fasa University of Medical Sciences /Volume 4 / No. 3.

18) Pooneh Nikuei, ,Kianoosh Malekzadeh, Rahman Mahdizadeh**, Razieh Mahdizadeh, Fatemeh Poordarvishi, Fouzieh Hajizadeh  and Foroogh Zahedi  (2015)  Double First Cousin Marriage and Genetic Disorders in South of IRAN,  American Journal of Life Science Researches,  Vol. 3, Issue 2, 140-143.

19)  Pooneh Nikuei, Kianoosh Malekzadeh , Rahman Mahdizadeh**, Razieh Mahdizadeh  ,Fouzieh Hajizadeh ,Foroogh Zahedi . (2015)  Genetic Counseling in South of IRAN. American Journal of Life Science Researches, Vol.3; Issue 2; pp. 144-147.

20)  Pooneh Nikuei, Kianoosh Malekzadeh**, Minoo Rajaei**,  Azim Nejatizadeh, Nasrin Ghasemi (2015) The imbalance in expression of angiogenic and antiangiogenic factors as candidate predictive biomarker in preeclampsia. Iran J. Reprod. Med Vol.13; No.5; pp: 251-262.

21) Habibollah Turki; Ahmad  Raeisi;  Kianoosh  Malekzadeh;  Amin Ghanbar-Nejad; Samaneh Zoghi;Mmasoud Yeryan; Masoumeh Abedi Nejad; Fatemeh Mohseni; Mohammad  Shekari** (2015) Efficiency of Nested-PCR in Detecting Asymptomatic Cases toward Malaria Elimination Program in an Endemic Area of Iran. Iran J Parasitol: Vol. 10, No. 1, pp.39-45.

22) Pooneh Nikuei, Kianoosh Malekzadeh, Minoo Rajaei, Yousef Shafeghati** (2015) Berardinelli-Seip Congenital Lipodystrophy:Report of an Iranian Girl with a Novel Mutation of BSCL2 Gene, Genetic in 3rd millennium; Vol.13; No.2; (9), pp. 4002-4005


Abstracts entitled

Date

Place

Symposium

Isolation and characterization of the Outer Membrane Proteins (OMP) of S.  typhimurium and studies their  immunoginicity

Dec.

2007

Tehran
Iran

5th National Biotechnology of Iran

Methylation patterns of DAPK and P16 promoters and their Impact on their expression in bladder cancer

Dec.

2008

New Delhi
India

International Symposium on
Novel Strategies for Targeted

Prevention and Treatment of Cancer

Hypermethylation mediated down-regulation of
TMS1 transcription in Human Uro-epithelial Cancer

Feb. 2009

Hydarabad
India

International Symposium on
Epigenetic modification on the Genome: Mechanisms and implication

Aberrant hypermethylation mediated down regulation of p16 and p15 transcription in childhood acute lymphoblastic leukemia (ALL) amomg north Indian population”

Sept. 2009

Philadelphia
 USA

International Symposium on
Oncology Translational Medicine and Drug Discovery Area

Biotechnology and its application in management of Genetic Disease

June 2011

 Bandar Abbas
Iran

Annual CME in

Diagnostic & Consulting in Genetic & Hereditary Disease

Low Prevalence of Asymptomatic Malaria in Endemic Area of Iran

Jan

2012

Kish
Iran

International Symposium on
Malaria Elimination

Tumoral RNA transfection in Dendritic Cells Derived from Stomach Cancer can play as a tool for immuno-gene therapy

Nov. 2011

Chandigarh
India

International Symposium of
Flowcytometry in Biomedical Applications

Low Prevalence of Asymptomatic Malaria in Endemic Area of Iran

Jan

2012

Kish Island

Iran

International Congress on Malaria Elimination

 

Biotechnology approach in treatment of Diabetic

Feb. 2012

 Bandar Abbas
Iran

National Symposium on
Novelties of Diabetes in Molecular aspects

Prevention of diabetic complication by oral Mg-administration in diabetic rats

Sept 2012

Kerman
 Iran

5th International Symposium on

 Iranian Biology Conference

Molecular Mechanism of Mg in decrease of glucose in diabetic Rats

Sept 2012

Kerman
 Iran

5th International Symposium on
Iranian Biology Conference

Metabolic  Heriditary Disorders: Neimen-Peak Disease

 Nov.

2012

 Bandar Abbas
Iran

Annual CME on

Genetic & Hereditary Prevalent Disease

Genetic Variants, Mutations  & Cancer

Feb. 2013

 Bandar Abbas
Iran

National Symposium on
Molecular Aspects of  Cancer

Polymorphisms of IFN-γ (+874A:T) and IL18(-137G:C) and its effect on  development, severity and treatment of Malaria

May 2013

Tehran
Iran

3rd Iranian Medical Genetics

The Effect of oral magnesium on expression of Glucose carrier 4 gene  in diabetic rats

July 2013

Tehran
Iran

8th National conference of Biotechnology of Iran

Relationship IL18 (-137G: C) and IFNγ (+874 A: T)  with host immune system sensitivity  to fight Plasmodium growth and severity of the malaria

July 2013

Tehran
Iran

8th National conference of Biotechnology of Iran

Hemoglobinpathies- The frontier & role of molecular monitoring

Dec.  2013

 Bandar Abbas
Iran

Annual CME on
Genetic & Hereditary Disease

Gangliosidosis GM1

Jan

2014

Yazd

Iran

7th Congress in Nerogenetics

Methylation mediated silencing of TMS1 in esophagus cancer and demethylation by low dose of Genistein

May

2014

Tehran
Iran

1st international Genetic Congress

Impact of Aberrant Promoter Hypermethylation on down-regulation of MTS2 and MTS1 in Childhood ALL

June

2014

Milan

2014

ESHGH - 2014

The impact of genetic counselling on prevention of mental retardation in south of Iran

June

2014

Milan

2014

ESHGH - 2014

Exact diagnostic of genetic syndromes can  help to predict of cancer in genetic counseling

June

2014

Bandar Abbas
Iran

Annual CME on
Molecular aspects on common cancer

Anti-Oxidant effects of herbal supplements  on seminal parameters

April

2015

Yazd

Iran

Reproductive Medicine

The role of miR-146a on NF-κB expression level in human umbilical vein endothelial cells under hyperglycemic condition

 

May

2015

Zanjan

Iran

6th International congress of Medical Student Research

Explanation of major biological subtypes and clonal expansion model of breast cancer by exploration of four mutation panel through Next-Generation Sequencing (NGS) technology

 

Sept.

2015

HydarAbad

India

2015 NextGen Genomics, Biology,

Bioinformatics and Technologies (NGBT) Conference

 

Ø Tumor cell- Monocyte-derived Dendritic Cell Hybrids and Applicability in Stomach Cancer: A Vaccine in Immunotherapy approach

Ø Molecular Analysis of β-Globin Gene Cluster Haplotypes in related to spectrum of common mutations of major β-thalassemia in Hormozgan Province             

MMRC-HUMS-2011

Ø Isolation & Molecular Identification of marine bacteria producing L-Asparaginase enzyme

MMRC-HUMS-2011

Ø Molecular investigation of cystic fibrosis mutations in Hormozgan Province

MMRC-HUMS-2011

Ø Investigation of molecular mechanism of oral magnesium administration on blood glucose in Diabetic Rats

MMRC-HUMS-2012

Ø Molecular investigation of IL-18 & IFN-γ immunogenes in Malaria patients in Hormozgan province –Iran and considering Sickle Cell Anemia

MMRC-HUMS-2012

Ø The impact of Grinstein in the hyper-methylation of TMS-I promoter in stomach cancer and its effect on expression

MMRC-HUMS-2012

Ø The Study of demethylating effect of Lycopene on expression of pro-apoptotic genes in Stomach

MMRC-HUMS-2013

Ø The role of miR-146 on the expression of TRAF-6 and IRAK-1 in Human umbilical vascular endothelial cells (HUVECs) during hyperglycemia

MMRC-HUMS-2013

Ø The role of miR-146 on rate of hyperglycemia-induced apoptosis, NF-κB, COX2, iNOS and ICAM1 in human umbilical vascular endothelial cells  

MMRC-HUMS-2013

Ø The role of miR-146 on the expression of NF-κB in Human umbilical vascular endothelial cells (HUVECs) during hyperglycemia

MMRC-HUMS-2013

Ø The impact of nano-conjugation of Geinstein to superparamagnetic iron-oxide nanoparticles as chemotherapeutic agent against cancer

MMRC-HUMS-2013

Ø The impact of Genistein on expression of Tumor Suppressor gene BTG3 in ALL through its inducing effect on Histon asetyl & Deasetyl transferase enzymes

  MMRC-HUMS-2014

Ø The impact of Genistein on expression of Tumor Suppressor gene E-cadherin in ALL through its inducing effect on histon modification

 MMRC-HUMS-2014

Ø Evaluation of Association Between Angiogenic Factor Flt1 and its Soluble Form  with Preeclampsia

MMRC-HUMS-2014

Ø The impact of Hif-1α in patients with preeclampsia

MMRC-HUMS-2014

Ø Evaluation the expression pattern of Dicer and Drosha genes in Preeclampsia

                                                                                 MMRC-HUMS-2014

Ø The effect of Mogza Capsule on expression profile of Antioxidant genes NOX5, XO, PRDX5 in oligospermic men

MMRC-HUMS-2014

Ø The effect of Mogza Capsule on expression of estrogen receptor ERα and cyp19 in oligospermic men

MMRC-HUMS-2014

Ø The Expression Profile of ERBB3 and its ligand NRG1 in depressed Patients in Hormozgan

MMRC-HUMS-2014


1)  Title:    Molecular Genetics of Bladder Cancer

ISBN:            978-81-906608-7-7              First Edition @ 2008        

Publisher:     Shahid Publications, 2253, Resham Wali Street, Kucha Chellan, Darya Ganj,

        New Delhi-110002 (INDIA)

Printing by:  New Print Centre, 2861/1, Kucha Chellan, Darya Ganj, NewDelhi-2 (INDIA)

Pages:           420 Pages

Language:    English

(This book included 420 pages, English language, and cover subjects regarding etiology, carcinogenesis model, molecular genetics, pathology & pathways, biomarkers & prognostic factors, molecular targets as futuristic treatment)

 

2)  Title:    Strategic Plan for Research Center

                  Chapter-1: Strategic Plan of Molecular Medicine Research Center

ISBN:            978-600-7710-00-5              First Edition @ 2014        

Publisher:     Hormozgan University for Molecular Medicine (HUMS) Press

                       Bandar Abbas, IRAN

Pages:            395 Pages

Language:      Farsi


ژنتیک پزشکی، زیست شناسی سلولی و مولکولی، ژنتیک پایه، ژنتیک ایمنی، ژنتیک سرطان، ژنتیک مولکولی، ژنتیک بیوشیمیایی انسان و اخلاق و ایمنی زیستی


  1. Molecular Genetics of diseases (particularly cancers)
  2. Epigenetic (Biomarkers + Pharmacogenomics) of diseases (particularly cancers)
  3.  Immuno-Cell therapy & Cancer Vaccine

new فایل های ارسالی
ردیفعنواندانلود فایل
No records to display.